banner

The information about p27/Kip1B phospho-Ser178 CDKN1B Polyclonal Antibody

Good morninf guys. Today i'll introduced you some information you may intersted in:
product name: p27/Kip1B phospho-Ser178 CDKN1B Polyclonal Antibody
Applications:IHC-P, WB-Ce
Immunogne:Rabbit polyclonal antibody raised against synthetic phosphopeptides of CDKN1B.
Description: p27/Kip1B phospho-Ser178 CDKN1B Polyclonal Antibody encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded p27/Kip1B phospho-Ser178 CDKN1B Polyclonal Antibody binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.