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Felypressin

Felypressin

[Products Name]        Felypressin
[Molecular Formula]     C46H65N13O11S2
[CAS No.]      56-59-7
[Synonyms] 
2-L-Phenylalanine-8-L-lysine-vasopressin;
N-[5-Amino-1-(carbamoylmethylcarbamoyl)pentyl]-1-[19-amino-13,16-dibenzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
[Product Description] 
Felypressin is a non-catecholamine vasoconstrictor that is chemically related to vasopressin, the posterior pituitary hormone. It is added to some local anaesthetics such as prilocaine in a concentration of 0.03 IU/ml. Felypressin is a V1 agonist, and will thus have affects at all V1 receptors.   It will, however, have its main physiological effects on vascular SMC's due to the form in which it is administered.
V1 receptors are found in various sites around the body. The major points include the CNS, Liver, Anterior Pituitary, Muscle (both vascular and     non-vascular smooth muscle), and Platelets (CLAMP).Another example of a V1 agonist is terlipressin - which is used in oesophageal varices.        
1.Purity (HPLC)                                      98%min.
2.Appearance                                  White powder
3.Single Impurity (HPLC)                    1.0%max
4.Amino Acid Composition                  ±10% of theoretical
5. Peptide Content (N%)                      ≥80.0%
6. Water Content (Karl Fischer)           ≤6.0%
7. Acetate Content (HPIC)                    ≤15.0%
8. MS (ESI)                                          Consistent
9. Mass Balance                               95.0~105.0%

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