Information of Terlipressin Acetate
Terlipressin (trade names Teripress by New Medicon Pharma and Glypressin by Ferring Pharmaceuticals) is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.
Indications for use include norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used in bleeding esophageal varices.
Item Name Terlipressin Acetate
Cas No. 14636-12-5
Molecular Formula C52H74N16O15S2
Molecular Weight 1227.37
Information of Terlipressin Acetate:
Purity (HPLC) 98.0%min.
Appearance White powder
Single Impurity (HPLC) 1.0%max
Amino Acid Composition ±10% of theoretical
Peptide Content (N%) ≥80.0%
Water Content(Karl Fischer) ≤10.0%
Specific Rotation (20/D) -95.0～-105.0°(c=1 1%HAc)
Acetate Content (HPIC) ≤15.0%
Mass Balance 95.0~105.0%